Ask a doctor - How does bone cancer spread?

Q. How does bone cancer spread?

Doctor Answer is medically reviewed by SecondMedic medical review team.

Answered by Secondmedic Expert

Bone cancer can spread through a process called metastasis, where cancer cells break away from the primary tumor and travel to other parts of the body through the bloodstream or lymphatic system. The spread of cancer to distant sites is a characteristic feature of malignant (cancerous) tumors, and it is a crucial factor influencing the stage and prognosis of the disease. Here's how bone cancer can spread:

1. Local Invasion:
- In the early stages, bone cancer cells may invade nearby tissues and structures within the bone. This local invasion can lead to the destruction of surrounding bone tissue and can cause symptoms such as pain, swelling, and changes in bone structure.

2. Bloodstream Spread (Hematogenous Metastasis):
- Cancer cells from the primary bone tumor can enter the bloodstream. Once in the bloodstream, these cells can travel to distant organs and tissues. Common sites for metastasis from bone cancer include the lungs, liver, and other bones.

3. Lymphatic Spread:
- Cancer cells can also spread through the lymphatic system, which consists of a network of vessels and lymph nodes. The lymphatic system plays a role in immune function and fluid balance. Cancer cells may enter the lymphatic vessels and travel to lymph nodes or other distant sites.

4. Formation of Secondary Tumors:
- Once cancer cells reach a distant organ or tissue, they may begin to grow and form secondary tumors, also known as metastatic tumors. The growth of metastatic tumors in these new locations can further compromise organ function and contribute to additional symptoms.

The ability of cancer cells to metastasize depends on various factors, including the type of cancer, the aggressiveness of the tumor, and the presence of specific molecular characteristics. Not all bone cancers metastasize, and the likelihood of metastasis varies among different types of bone cancer.

It's important to note that the spread of cancer is a complex process, and not all cancer cells that enter the bloodstream or lymphatic system successfully form metastatic tumors. Some may be eliminated by the immune system, while others may remain dormant for an extended period before becoming active.

Early detection and treatment of bone cancer are critical for preventing or managing metastasis. Regular monitoring and follow-up care after treatment are essential to detect any signs of recurrence or metastasis and to adjust the treatment plan accordingly.