Q. Does high PSA levels mean a sign of prostate cancer?
Doctor Answer is medically reviewed by SecondMedic medical review team.
Yes, high PSA levels can be a sign of prostate cancer in some cases. The exact cutoff for what is considered to be an elevated PSA level differs between organizations and individuals, but generally any reading above 4 ng/mL may indicate a potential problem.
The Prostate-Specific Antigen (PSA) test is one of the most reliable tests available for detecting prostate cancer, since it measures the amount of PSA in the blood and then provides healthcare providers with an indication as to whether or not more advanced testing should be done. If a man’s PSA levels are high, he should pursue further testing methods such as transrectal ultrasound-guided biopsy or MRI imaging.
It’s important to remember though that not all high PSA readings are caused by prostate cancer; they can also result from benign prostatic hyperplasia (BPH), or enlarged prostate caused by benign tissue growth within the gland; infection in the urinary tract; physical activities such as biking or riding horses frequently; and even simply age. There isn’t one single definitive test that will determine if someone has prostate cancer—it takes a combination of results and additional testing to make an accurate diagnosis.
In addition to measuring levels of total PSA in the blood, doctors often measure free PSA (the percentage of noncomplexed or unbound form found in serum). A low free-PSA ratio usually indicates higher risk for getting this type of cancer – although again nothing is certain until other tests are conducted.. Therefore if you have elevated PSAs from your annual physical checkup talk with your doctor about having further assessment because early detection makes treatment significantly easier than later diagnoses .