Q. What is the cause of exophthalmos in thyrotoxicosis?
Doctor Answer is medically reviewed by SecondMedic medical review team.
Exophthalmos is a medical condition that occurs when the eyeballs protrude outward from their sockets, giving the eyes a bulging appearance. It is most commonly caused by hyperthyroidism, otherwise known as thyrotoxicosis.
Hyperthyroidism is an endocrine disorder characterized by excessive production of thyroid hormone from the thyroid gland. This overproduction of hormone can occur due to Graves’ disease (an autoimmune disorder) or toxic nodular goiter (enlarged thyroid in which one or more lumps produce excess hormones). When these conditions are present, it results in an increase of intracranial pressure and causes exophthalmos.
The symptoms of exophthalmos with thyrotoxicosis include swelling around the eyelids and eyes that appear to “stare” outward, typically accompanied by vision problems such as double vision or blurred vision. As exophthalmos progresses, it can lead to painful deep-set wrinkles in the skin near the eyes and droopy lower eyelids called lagopthalmus.
For successful treatment of this condition and its accompanying symptoms, doctors usually prescribe medications like methimazole or propylthiouracil to reduce hyperthyroidism levels; radioiodine therapy to destroy overactive thyroid cells; surgical interventions such as thyroidectomy; beta blockers to slow down heart rate; steroids like prednisone for inflammation reduction; and/or radiation therapy if needed for rare cases where other treatments have failed. With proper diagnosis and treatment options available for patients suffering from exophthalmos caused by thyrotoxicosis , people now have better chances at managing this potentially dangerous eye problem successfully before any permanent damage occurs.