What is IV meth use and vascular pain in the legs?

Injection of methamphetamine (crystal meth) can result in direct damage to the blood vessels in your legs and feet. This is called vascular pain.

IV meth use can also cause a condition called compartment syndrome. This is a build-up of pressure in the muscles, which cuts off the blood supply to the area. Gangrene can then set in, and if it's not treated, the limb may have to be amputated.