Drotin M 80mg250mg Tablet 10s is a combination medication containing Drotaverine and Mefenamic Acid It is used to treat various conditions characterized by muscle spasms and pain This medication provides relief for stomach pain associated with spasms and abdominal discomfort It also helps with spasms in the gastrointestinal tract related to irritable bowel syndrome Drotin M is effective in addressing muscle spasms in the uterus during menstruation and labor It can alleviate chest pain caused by muscle spasms and help with gallstones and renal colic Drotaverine works by inhibiting phosphodiesterase enzyme IV while Mefenamic Acid reduces inflammation Follow the prescribed dosage and instructions Possible side effects include hypotension headache tachycardia nausea vertigo vomiting abdominal distress and headache Drotaverine is contraindicated in severe renal hepatic and cardiac impairment while Mefenamic Acid is contraindicated in inflammatory bowel disease and peptic ulcer If a dose is missed follow the appropriate instructions