Triple Antigen Vaccine is a combination of three vaccines used to prevent diphtheria, tetanus, and whooping cough. It stimulates the immune system to act against microorganisms to prevent such infections. Triple Antigen Vaccine is to be administered by a healthcare professional. It may cause redness, pain, and swelling at the site of injection. However, this is temporary and usually resolves on its own. Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.