Nervepen Gel is a prescription medicine used for the treatment of neuropathic pain. It works by first cooling and then warming up the skin. Thus, it calms the damaged or overactive nerves by acting on the brain, thereby decreasing the sensation of pain. Nervepen Gel is for external use only. You should use this in the dose and duration advised by your doctor. Clean and dry the affected area before applying this medicine to the skin. You should always wash your hands after applying it unless hands are the affected area.