Q. What are the potential side effects of uterine cancer treatments?

Doctor Answer is medically reviewed by SecondMedic medical review team.

Answered by Secondmedic Expert

The potential side effects of uterine cancer treatments can vary depending on the type of treatment, the stage of cancer, and individual factors. It's important to note that not everyone will experience the same side effects, and their severity can differ from person to person. Common treatments for uterine cancer include surgery, radiation therapy, chemotherapy, hormone therapy, targeted therapy, and immunotherapy. Here are potential side effects associated with each:

1. Surgery:
- Hysterectomy (removal of the uterus):
- Short-term pain and discomfort.
- Temporary fatigue and weakness.
- Changes in sexual function and libido.
- Early menopause if the ovaries are also removed.

2. Radiation Therapy:
- External Beam Radiation:
- Fatigue.
- Skin changes (redness, itching, or peeling) in the treated area.
- Nausea and vomiting (if radiation is directed toward the abdomen).
- Bowel or bladder irritation.
- Brachytherapy:
- Vaginal irritation or discharge.
- Short-term discomfort during the placement of the radiation sources.

3. Chemotherapy:
- General Side Effects:
- Fatigue.
- Nausea and vomiting.
- Hair loss.
- Changes in appetite.
- Risk of infection due to lowered immune function.
- Specific to Certain Drugs:
- Peripheral neuropathy (numbness or tingling in the hands and feet).
- Kidney or liver problems.
- Bone marrow suppression leading to low blood cell counts.

4. Hormone Therapy:
- Hot flashes and night sweats.
- Changes in libido.
- Vaginal dryness.
- Mood swings.

5. Targeted Therapy:
- Skin Rash or Changes: Some targeted drugs can cause skin-related side effects.
- Gastrointestinal Issues: Diarrhea or other digestive problems.
- Liver Problems: Elevated liver enzymes may occur.

6. Immunotherapy:
- Fatigue.
- Flu-like Symptoms: Fever, chills, muscle aches.
- Skin Reactions: Rash or itching.

It's crucial for individuals undergoing treatment to communicate openly with their healthcare team about any side effects experienced. Healthcare providers can offer supportive care to manage or alleviate side effects, and adjustments to treatment plans may be considered if side effects become severe.

Supportive care measures may include medications to control nausea, pain management, counseling or support groups to address emotional concerns, and interventions to manage treatment-related symptoms. Every patient's experience is unique, and healthcare providers work closely with individuals to tailor treatment plans and provide the best possible care.