Answered by SecondMedic Expert
Oncologist · Cancer / Oncology / Cancer Surgery
Breast cancer typically does not cause detectable changes in the blood. Blood tests to diagnose breast cancer are not recommended for routine screening or diagnosis, as there is no single laboratory test that can reliably detect it.
However, certain tumors release protein markers into the bloodstream which can be detected by specialized lab tests such as a CA 27.29 tumor marker test or circulating tumor cell (CTC) testing. These specialized tests have been used to identify recurrence or metastatic spread of some types of breast cancers, but cannot currently detect an early stage primary cancer and should only be used after a diagnosis has been made using traditional medical techniques such as biopsy and imaging scans like mammography or MRI.
If someone has already been diagnosed with breast cancer through a tissue biopsy, their doctor may recommend periodic CTC testing throughout their treatment regimen to monitor how well their therapy is working and when further intervention might be necessary if the CTC count rises significantly above baseline levels. Better understanding of the molecular landscape of individual patient’s tumors will help improve accuracy of these tests in detecting breast cancer earlier than ever before— potentially making these kinds of blood-based diagnostic tools part of regular screening protocols someday soon!