Answered by SecondMedic Expert
Neurologist · Neurology
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The causes of ankylosing spondylitis are unknown, but there are several theories. One theory is that ankylosing spondylitis is caused by a combination of environmental and genetic factors. Another theory suggests that an infection or autoimmune reaction may trigger the disease. Some researchers believe that a defect in the gene HLA-B27 may make some people more likely to develop ankylosing spondylitis.
