Q.

Can pancreas be replaced to cure diabetes?

Asked by KAVITA MISHRA ·

Medically reviewed by SecondMedic medical review team

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Answered by SecondMedic Expert

Nephrologist · Transplant Surgery/ Liver /Kidney transplant

Yes, a person with type 1 diabetes can have their pancreas surgically replaced to cure the condition. This treatment is known as “pancreas transplantation” and involves replacing the diseased pancreas of an individual with a healthy organ from a donor. Pancreas transplantation has been widely used for over 30 years, and in many cases, it has had good success rates in helping people achieve very good long-term control of their diabetes.

Pancreatic tissue transplants are extremely complex procedures that require special expertise and advanced medical technology (such as specialized methods for harvesting donor organs). When successful, the transplanted pancreatic cells produce insulin that helps regulate blood glucose levels in those individuals who have lost the ability to make insulin themselves due to diabetic complications or autoimmune disease. Generally speaking, it takes several months after surgery before any improvement is seen regarding blood sugar levels since time is required for the new pancreatic cells to begin producing insulin on a regular basis.

It's important to note that while this procedure may be helpful for some patients with type 1 diabetes, it should not be considered as an option by those suffering from type 2 diabetes—the most common form of diabetes—since they are able to make some level of insulin themselves without needing replacement tissue or medication intervention.
In addition, although convincing benefits have been shown with clinical trials involving pancreas transplants in individuals with type 1 diabetes who also need kidney transplants due to end-stage renal failure caused by bad outcomes from uncontrolled DM1 (diabetic ketoacidosis), at present there is no evidence that replacing both kidneys and pancreases would result in better overall outcomes than only having one kidney replaced.
Therefore if you are considering this option speak with your doctor about weighing out all pros and cons when making such decisions about life altering treatments such as these—and remember ultimately it’s up to you what course is best taken!

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