Q. What conditions or diseases can cause abnormalities in liver function test (LFT) results?
Doctor Answer is medically reviewed by SecondMedic medical review team.
Liver function tests (LFTs) are crucial for assessing the health of your liver. Abnormalities in LFT results can signal various conditions affecting the liver. One common cause is hepatitis, which can elevate liver enzymes like ALT and AST. Fatty liver disease (NAFLD or NASH) can also impact LFTs due to liver inflammation and damage.
Liver cirrhosis is another condition that significantly alters LFT results. As the liver becomes scarred and dysfunctional, it affects albumin and bilirubin levels. Alcohol-related liver disease can lead to elevated liver enzymes and abnormal LFTs.
Certain medications and toxins can cause liver function test abnormalities. For example, acetaminophen overdose can result in elevated liver enzymes. Autoimmune hepatitis is a condition where the immune system attacks the liver, affecting LFT markers.
Gallbladder diseases such as cholecystitis or choledocholithiasis (gallstones) can impact LFT results due to bile flow disturbances. Pancreatitis can also affect liver function tests due to shared bile ducts and enzymes.
Certain cancers, including liver cancer or metastasis to the liver, can cause abnormal LFT results. These conditions may elevate specific liver enzymes or affect liver protein synthesis.
It's important to note that while abnormal LFTs can indicate liver problems, further tests are usually needed for a definitive diagnosis. Always consult with a healthcare professional for proper evaluation and management based on your specific situation.
Related Questions
-
Hepatobiliary &Pancreas Surgery How effective are pancreas transp
-
What causes itching sensation? | Secondmedic
-
What causes ascites? | Secondmedic
-
What role does the lymphatic system play in pedal edema? | Secondmedic
-
What are the common causes of pedal edema? | Secondmedic
-
Are there different types of jaundice? | Secondmedic