BRCA1/2 Full gene sequencing

BRCA1/2 full gene sequencing

Mapmygenome's BRCAMap is a targeted next generation sequencing(NGS) Panel for BRCA 1 & BRCA 2 full gene sequencing to assess the BRCA mutations that are responsible for the majority of hereditary breast and ovarian cancers.

 

BRCA genes are popularly known as breast cancer, early onset genes. They are “tumor suppressors'' in nature. BRCA genes repair damages or double stranded breaks in DNA and restore genomic integrity of human cells. Hence they play a vital role in maintaining normal cell growth in the body . Defective BRCA genes account for nearly 5-10% of breast cancer cases, while the rest are sporadic in nature.

 

Who should be tested?

• Strong family history of breast, ovarian, fallopian tube, peritoneal, prostate, or pancreatic cancer (BRCA1&2 mutations are inherited, family members with either BRCA1 or BRCA2 mutations usually share the same mutation.)

• Personal history of Breast/ovarian cancers and meets the criteria related to : age of diagnosis, type of cancer/Bilateral Cancers ancestry.

• Personal/family history of ovarian, fallopian tube, or primary peritoneal cancer.

• History of breast cancer in Males.

• A relative with a known deleterious mutation in BRCA1 or BRCA2 genes.

• Ashkenazi Jewish or Eastern European ancestry.

 

Features

• High diagnostic yield with coverage of 500-600x on Illumina NGS platform

• Best in class Bioinformatics pipeline for most accurate analysis by our experienced Bioinformatics team.

• Can be performed on both somatic samples &  Germline samples

 

Booking Procedure:

• Fill the booking form on the right side with Name, Address, Mobile no.

• Blood/Saliva samples will be collected from your Home address. 1 hrs fasting is required.

• You need to make the payment by cash to Genetic Testing when Technician comes to pick up the samples OR Pay online after confirmation of booking.

• Reports will be shared within 3-4 weeks on your email address mentioned while booking.

 

Report 

Report generation with quick TAT

99?curacy

Fast Therapeutic Benefits

Easy to read & self-explanatory report

Booking Procedure:

• Fill the booking form on right side with Name, Address, Mobile no.
• Blood/Urine samples will be collected from your Home address. 10-12 hrs fasting is required.
• You need to make the payment by cash to Genetic Testing when Technician comes to pick up the samples OR Pay online after confirmation of booking.
• Reports will be couriered at your residence in 3-4 working days if hardcopy is opted. We will email the reports within 48-72 hrs on your email address mentioned while booking.

• Sample pickup at home
• Online reports within 48 hours