Q. What are the first signs of multiple myeloma?

When it comes to multiple myeloma, the early signs can be subtle, but it's crucial to catch them early. Here are some key things to keep an eye on:

1. Bone pain:
One of the initial signs is bone pain, usually in the back, hips, or skull. It can be persistent and unrelated to any specific injury. If you're noticing discomfort that doesn't seem to go away, it's worth checking in with your doctor.

2. Fatigue:
Feeling more tired than usual? Multiple myeloma can lead to fatigue, and it's not your typical "I had a busy day" tiredness. It's a persistent, lingering fatigue that doesn't improve with rest. Don't brush it off; let your doctor know.

3. Weakness or numbness:
Some folks experience weakness or numbness, especially in the legs. If you're finding it difficult to perform tasks that were once easy or if you're noticing strange sensations, it's time to get a medical opinion.

4. Frequent infections:
Multiple myeloma affects your immune system, making you more susceptible to infections. If you're getting sick more often than usual, or if infections seem to linger longer than they should, this could be a red flag.

5. Unexplained weight loss:
Losing weight without trying is always a signal to investigate. If the pounds are dropping off without changes in diet or exercise, it's essential to delve deeper into the potential causes, including multiple myeloma.

6. Excessive thirst and urination:
Some people with multiple myeloma experience increased thirst and more frequent trips to the bathroom. If you notice changes in your bathroom habits or unexplained thirst, don't ignore it—get it checked out.

7. Nausea and constipation:
Digestive issues like nausea and constipation can also be early signs. While these symptoms can be caused by various factors, when combined with other potential myeloma indicators, they warrant a closer look.

8. Abnormal blood tests:
Sometimes, multiple myeloma is detected through routine blood tests. Elevated levels of certain proteins or a low red blood cell count can be indicators. Regular check-ups and blood work are essential for catching these abnormalities.

9. Hypercalcemia symptoms:
High levels of calcium in the blood, known as hypercalcemia, can occur in multiple myeloma. Symptoms may include excessive thirst, frequent urination, and confusion. If you experience any of these, it's time to seek medical attention.

Remember, everyone's body is unique, and symptoms can vary. If you notice persistent changes or a combination of these signs, don't hesitate to reach out to your healthcare provider. Early detection and intervention can make a significant difference in managing multiple myeloma effectively. Your health is important, so stay proactive and keep those lines of communication with your doctor open!